Hepatitis C Medicines

Daclatasvir 60mg is an inhibitor of nonstructural protein 5A (NS5A), a multifunctional protein that is an essential component of the HCV replication complex. Daclatasvir inhibits both viral RNA replication and virion assembly.

Pharmacokinetics
The pharmacokinetic properties of Dasikast (Daclatasvir) were evaluated in healthy adult subjects and in patients with chronic HCV. Following multiple oral doses of Daclatasvir 60 mg once daily in combination with peg interferon alfa and ribavirin in treatment naive patients with genotype 1 chronic HCV, the geometric mean (CV%) Daclatasvir Cmax was 1534 (58) ng/ml, AUC0-24h was 14122 (70) ng*h/ml, and Cmin was 232 (83) ng/ml.

Indications & Usage
Dacikast is indicated in combination with Sofosbuvir for the treatment of patient with chronic hepatitis C virus (HCV) genotype 3 infection.

Dosage & Administration:
Treatment with Dacikast should be initiated and monitored by a physician experienced in the management of chronic hepatitis C. The recommended dose of Dacikast is 60 mg once daily, to be taken orally with or without meals. Dacikast must be administered in combination with other medicinal products. The Package Inserts of the other medicinal products in the regimen should also be consulted before initiation of therapy with Dacikast.

Contraindications:
Hypersensitivity to the active substance or to any of the Excipients Co-administration with medicinal products that strongly induce cytochrome P450 3A4 (CYP3A4) and P-glycoprotein transporter (P-gp) and thus may lead to lower exposure and loss of efficacy of Daclatasvir. These active substances include but are not limited to phonation, carbamazepine, oxcarbazepine, phenobarbital, rifampicin, rifabutin, rifapentine, systemic dexamethasone, and the herbal product St John’s wort (Hypericum perforatum).

Overdosage
There is limited experience of accidental overdose of Daclatasvir in clinical trials. In phase 1 clinical trials, healthy subjects who received up to 100 mg once daily for up to 14 days or single doses up to 200 mg had no unexpected adverse reactions. There is no known antidote for overdose of Daclatasvir. Treatment of overdose with Daclatasvir should consist of general supportive measures, including monitoring of vital signs, and observation of the patient’s clinical status. Because Daclatasvir is highly protein bound (99%) and has a molecular weight >500, dialysis is unlikely to significantly reduce plasma concentrations of Daclatasvir.

Store below 25°C. 

• Delivery Time: 1 to 2 Days

With our in-depth knowledge and rich industry experience in this field, we are highly engaged in exporting, retailing, wholesaling and supplying a qualitative Mydekla Tablet for our esteemed clients. Processed employing advanced technology and using premium quality chemical compounds, offered tablet should only be used under proper medical guidance and advice. In order to maintain the effectiveness, our quality examiners test this tablet on various parameters.

Features:

• Highly effective
• Long shelf life
• Balanced composition

Other Details: 28 Tablets.

• Delivery Time: 10 to 14 days

Velakast Tablet is a prescribed medication that combines two antiviral drugs and is commonly used to treat chronic hepatitis C virus (HCV) infection. This medicine is effective in combating the virus and resolving the infection.

When taking Velakast Tablet, it is important to follow the prescribed dosage and duration, taking it at the same time each day. While it can be taken with or without food, it is recommended not to exceed the prescribed dose. Inform your doctor of any pre-existing health conditions, particularly liver or kidney disease. It is also essential to avoid or limit alcohol consumption as it can be harmful when taken alongside this medicine. To ensure optimal results, it is essential to complete the entire course of the medication as prescribed.

• Delivery Time: 1 to 2 Days

 

Resof Total Tablet is a prescribed medication that combines two antiviral drugs and is commonly used to treat chronic hepatitis C virus (HCV) infection. This medicine is effective in combating the virus and resolving the infection.

When taking Resof Total Tablet, it is important to follow the prescribed dosage and duration, taking it at the same time each day. While it can be taken with or without food, it is recommended not to exceed the prescribed dose. Inform your doctor of any pre-existing health conditions, particularly liver or kidney disease. It is also essential to avoid or limit alcohol consumption as it can be harmful when taken alongside this medicine. To ensure optimal results, it is essential to complete the entire course of the medication as prescribed.

 

• SoviHep (Sofosbuvir) which is a drug used as part of antiviral therapy against chronic hepatitis C virus, this drug is directly targets the Hep C virus to stop it from making copies of itself in the liver and makes it harder for the virus to multiply
• SoviHep (Sofosbuvir) must be used in combination with other HCV medications such as Pegylated and Ribavirin

• Delivery Time: 7 to 14 days

Sofokast plus tablets, which contain 400 mg Sofosbuvir is a nucleotide polymerase inhibitor, and includes antiviral drugs direct action. sofosbuvir is exposed to have a high barrier to growth resistance and inhibits the Cb NS5B Hep protein. Thus, Sofosbuvir interferes with the enzyme RNA polymerase by a cell worker who can perform the reproduction process. Consequently, Sofosbuvir stops hepatitis C virus replication and reduces the amount of Hep C virus in the liver. Sofosbuvir also acts to reduce liver damage and improve liver function.

Sofokast plus tablets also contains daclatasvir, a direct-acting antiviral drug that is indicated for a patient affected by hepatitis C virus infection. It will target the Hep C virus and stops numerous steps in the HCV reproduction process by preventing viral particles from making copies themselves, and helps the body remove the virus from the blood.

Note:

• DaciHep is a prescription drug and should be used under proper medical guidance and advice
• The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers
• Keep all medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed

How it works:
Sofosbuvir is an antiviral drug that belongs to a class of medicines called nucleotide polymerase inhibitors. It inhibits an enzyme RNA polymerase which is essential for viral replication and thus decreases the amount of Hepatitis C virus in the body thereby resulting in less liver damage and improved liver function.

Common side effects:
Nausea, Pale colored skin, Back pain, Chills, Diarrhoea, Fatigue, Weakness, Fever, Headache, Insomnia, Loss of appetite, Mouth ulcer, Muscle pain, Muscle cramp, Rash, Itching, Sores, Ulcer

 

Velpanat Tablet is a prescribed medication that combines two antiviral drugs and is commonly used to treat chronic hepatitis C virus (HCV) infection. This medicine is effective in combating the virus and resolving the infection.

When taking Velpanat Tablet, it is important to follow the prescribed dosage and duration, taking it at the same time each day. While it can be taken with or without food, it is recommended not to exceed the prescribed dose. Inform your doctor of any pre-existing health conditions, particularly liver or kidney disease. It is also essential to avoid or limit alcohol consumption as it can be harmful when taken alongside this medicine. To ensure optimal results, it is essential to complete the entire course of the medication as prescribed.

 

MyHep contains the active ingredient Sofosbuvir. It is a generic brand of anti-viral medication used to treat Hepatitis C virus. MyHep is manufactured by Mylan Pharmaceuticals. Sofosbuvir can help the immune system and the liver recover from a Hepatitis C infection.

Specifications:

• Active Ingredients: Sofosbuvir
• Manufacturer: Mylan
• Use: In liver infection

MOQ 28 Tab

With our in-depth knowledge and rich industry experience in this field, we are highly engaged in exporting, retailing, wholesaling and supplying a qualitative NATDAC Tablet for our esteemed clients. Processed employing advanced technology and using premium quality chemical compounds, offered tablet should only be used under proper medical guidance and advice. In order to maintain the effectiveness, our quality examiners test this tablet on various parameters.

Features:

• Highly effective
• Long shelf life
• Balanced composition

 

Other Details: 28 Tablets.

• Delivery Time: 7 to 14 days

Hepcinat Plus tablet is an antiviral medication. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time. These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.

 

The dosage should be determined by the doctor based on your age, overall medical history and current condition. The usual dose in adults for treating chronic hepatitis C is 60 mg, taken orally once daily for a period of 12 weeks.

Sofokast is manufactured under license from Gilead Sciences Ireland UC.

Indications for use of the drug:
The drug Sofosbuvir 400 mg is prescribed for patients with hepatitis C when the disease has passed into a chronic form. A combined approach is used for the effectiveness of treatment. It is possible to use medicament in cases when the patient has HIV in addition to hepatitis.

Contraindications to taking the drug “Sofosbuvir”:
The drug is not used for hypersensitivity to substances that are present in its composition. Despite the fact that the drug does not affect fertility, it is rarely prescribed to women in their reproductive years. The use of the drug during pregnancy and breastfeeding is not recommended, as it can be harmful to the child. When pregnancy occurs, the combination of Sofosbuvir with such drugs as Interferon alfa and Ribavirin may have a negative effect on its course. For this reason, during the period of treatment, the child’s bearing is undesirable. The experiments, during which the drug “buy sofosbuvir online” was tested in animals, showed that this drug has a slightly negative impact on the offspring. Before you start taking it, you should carefully study the instructions for the drug and consult with a specialist.

Side Effect:

• Side effects are fully dependent on those drugs that are used in addition to Sofosbuvir, t. the main component can cause an only headache and mild weakness.
• We describe the possible negative effects with different combinations of Sofosbuvir in the course of treatment at 12 weeks:
• Ribavirin, more than 10% of cases. Blood can decrease the concentration of hemoglobin and increase the bilirubin index, insomnia, nausea may occur.
• Ribavirin up to 10 % Anemia, depression, dyspnea, cough, disorders in the digestive tract, hair loss, itching on the skin, cramps, pains in the joints and back and some others.
• Interferon alfa and Ribavirin, more than 10% of cases. There is anemia, a decrease in the number of platelets and lymphocytes, impaired appetite, dizziness, insomnia, shortness of breath, diarrhea, vomiting, nausea, increased bilirubin, myalgia, joint pain, irritability, rashes and itching on the skin, fever,
• Interferon alfa and ribavirin, less than 10 %. Depression, anxiety, weight loss, migraine, impaired vision, memory and concentration, constipation, reflux, cramps, back and chest pain, asthenia, hair loss.

• Delivery Time: 1 to 2 Days

 

Sovihep V Tablet is a prescribed medication that combines two antiviral drugs and is commonly used to treat chronic hepatitis C virus (HCV) infection. This medicine is effective in combating the virus and resolving the infection.

When taking Sovihep V Tablet, it is important to follow the prescribed dosage and duration, taking it at the same time each day. While it can be taken with or without food, it is recommended not to exceed the prescribed dose. Inform your doctor of any pre-existing health conditions, particularly liver or kidney disease. It is also essential to avoid or limit alcohol consumption as it can be harmful when taken alongside this medicine. To ensure optimal results, it is essential to complete the entire course of the medication as prescribed.

Hepcvel Tablet is a prescribed medication that combines two antiviral drugs and is commonly used to treat chronic hepatitis C virus (HCV) infection. This medicine is effective in combating the virus and resolving the infection.

When taking Hepcvel Tablet, it is important to follow the prescribed dosage and duration, taking it at the same time each day. While it can be taken with or without food, it is recommended not to exceed the prescribed dose. Inform your doctor of any pre-existing health conditions, particularly liver or kidney disease. It is also essential to avoid or limit alcohol consumption as it can be harmful when taken alongside this medicine. To ensure optimal results, it is essential to complete the entire course of the medication as prescribed.

We are offering Hepcinat-LP Ledipasvir & Sofosbuvir Tablets to our clients.

Note:

• Keep out of reach of children
• Store below 30 Degree C

Why is this medication prescribed?

Daclatasvir is used along with another medication (sofosbuvir [Solvadi]) to treat a certain type of chronic hepatitis C (an ongoing viral infection that damages the liver). Daclatasvir is in a class of antiviral medications called hepatitis C virus (HCV) NS5A inhibitors. It works by stopping the virus that causes hepatitis C from spreading inside the body. It is not known if daclatasvir prevents the spread of hepatitis C to other people.

How should this medicine be used?

Daclatasvir comes as a tablet to take by mouth. It is usually taken with or without food once a day. Daclatasvir must be taken in combination with sofosbuvir, usually for 12 weeks. Take daclatasvir at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take daclatasvir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continue to take daclatasvir even if you feel well. Do not stop taking daclatasvir or sofosbuvir without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information

• Delivery Time: 10 To 14 Days

Sofosbuvir(400 Mg)Uses Resof 400mg tablet is used in combination with other antiviral drugs for treatment of patients with viral infection that damages the liver (Hepatitis C) including those patients who have human immunodeficiency virus (HIV) infection or liver cancer or are awaiting a liver transplant.How it works Resof 400mg tablet is an antiviral drug that belongs to a class of medicines called nucleotide polymerase inhibitors. It inhibits an enzyme RNA polymerase which is essential for viral replication and thus decreases the amount of Hepatitis C virus in the body thereby resulting in less liver damage and improved liver function.Common side effectsNausea, Pale colored skin, Back pain, Chills, Diarrhoea, Fatigue, Weakness, Fever, Headache, Insomnia, Loss of appetite, Mouth ulcer, Muscle pain, Muscle cramp, Rash, Itching, Sores, Ulcer

• Delivery Time: 10 TO 14 DAYS

Being an authentic entity, we are engaged as trader, supplier and exporter of Dalsi Clear 60mg (Daclatasvir Tablets) in Delhi, India available with following details.

Details:

• Brand Name: DalsiClear
• Content: Daclatasvir Dihydrochloride
• Manufactured by: Abbott India Ltd.
• Strengths: 60 mg
• Form: Tablets
• Packing: Pack of 28 Tablets

Side Effects:
Most common side effects of Daclatasvir include Headache and Fatigue.

Drug interactions:
Daclatasvir when used in combination treatment with Sofosbuvir may result in slowing of the heart rate (pulse) along with other symptoms when taken with Amiodarone, a medicine used to treat certain heart problems.

Cimivir 400 mg tablet is an antiviral drug that belongs to a class of medicines called nucleotide polymerase inhibitors. It inhibits an enzyme RNA polymerase which is essential for viral replication and thus decreases the amount of Hepatitis C virus in the body thereby resulting in less liver damage and improved liver function.

Common side effects:
Nausea, Pale colored skin, Back pain, Chills, Diarrhoea, Fatigue, Weakness, Fever, Headache, Insomnia, Loss of appetite, Mouth ulcer, Muscle pain, Muscle cramp, Rash, Itching, Sores, Ulcer

Viroclear 400 mg tablet is an antiviral drug that belongs to a class of medicines called nucleotide polymerase inhibitors. It inhibits an enzyme RNA polymerase which is essential for viral replication and thus decreases the amount of Hepatitis C virus in the body thereby resulting in less liver damage and improved liver function.

Common side effects:
Nausea, Pale colored skin, Back pain, Chills, Diarrhoea, Fatigue, Weakness, Fever, Headache, Insomnia, Loss of appetite, Mouth ulcer, Muscle pain, Muscle cramp, Rash, Itching, Sores, Ulcer

We are offering Daclacure Daclatasvir Dihydrochloride Tablets to our clients.

We are offering Virpas Ledipasvir & Sofosbuvir Tablets to our clients.

Ribavirin (Ribasure) is a synthetic nucleoside analogue which has shown in vitro activity against some RNA and DNA viruses. The mechanism by which Ribasure in combination with other medicinal products exerts its effects against HCV is unknown.

Pharmacodynamics:
The antiviral activity of Ribavirin in the HCV-replicon is not well understood and has not been defined because of the cellular toxicity of Ribavirin.

Resistance HCV genotypes show wide variability in their response to pegylated recombinant human interferon/ribavirin therapy. Genetic changes associated with the variable response have not been identified.

Cross-resistance:
There is no reported cross-resistance between pegylated/non-pegylated interferons and Ribavirin.

Pharmacokinetics:
Ribavirin is absorbed rapidly following oral administration of a single dose (mean Tmax= 1.5 hours), followed by rapid distribution and prolonged elimination phases (single dose half-lives of absorption, distribution and elimination are 0.05, 3.73 and 79 hours, respectively). Absorption is extensive with approximately 10 % of a radiolabelled dose excreted in the faeces. However, absolute bioavailability is approximately 45 %-65 %, which appears to be due to first pass metabolism.

• Delivery Time: 7 to 14 Days

Ledikast is a fixed-dose combination tablet containing ledipasvir and sofosbuvir for oral administration. Ledipasvir is an HCV NS5A inhibitor and sofosbuvir is a nucleotide analog inhibitor of HCV NS5B polymerase.

The tablet includes the following inactive ingredients: Colloidal silicon dioxide, copovidone, croscarmellose sodium, lactose monohydrate, magnesium stearate, and microcrystalline cellulose.

The tablet is film-coated with a coating material containing the following inactive ingredients: Yellow Oxide of Iron, polyethylene glycol, polyvinyl alcohol, talc, FD&C Blue #2 and titanium dioxide IP.

Based on drug interaction studies conducted with individual drugs Ledipasvir or Sofosbuvir or combination of Ledipasvir + Sofosbuvir, no clinically significant drug interactions have either been observed or are expected when Ledipasvir + Sofosbuvir is used with the following drugs individually: abacavir, atazanavir/ritonavir, cyclosporine, darunavir/ ritonavir, efavirenz, emtricitabine, lamivudine, , oral contraceptives, pravastatin, raltegravir, rilpivirine, tacrolimus, tenofovir disoproxil fumarate, or verapamil. 

Ledikast is manufactured under license from Gilead Sciences Ireland UC.

We have achieved a distinct position in the market by wholesaling and exporting a superior quality Hepcvir Tablet. Used in combination with other antiviral medicines to reduce the amount of hepatitis C virus (HCV) in the body to help the liver recover, offered tablet is hygienically processed using the best quality chemical compounds and modern technology under the vigilance of vendors’ professionals in line with set industry standards. Furthermore, this tablet is tested on varied parameters by our quality examiners so as to ensure its quality.

Features:

• Accurate composition
• Highly effective
• No side effects

Other Details: 15 Tablets.

• Delivery Time: 7 To 14 Days

Hepcvir L is a combination of two hepatitis C virus (HCV) antiviral drugs in a single form. Each single tablet contains ledipasvir and sofosbuvir.

Uses:

• Hepcvir L is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. 
• It may sometimes be used with another antiviral medication (ribavirin). 
• These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover.

Common Side Effects:

• Tiredness, headache, nausea, diarrhea, or difficulty sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
• A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
• This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions:

• Before taking ledipasvir/sofosbuvir, tell your doctor or pharmacist if you are allergic to either of the drugs; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease.

• Delivery Time: 7 to 14 Days